• About Us
  • Advertise
  • Contact Us
  • DMCA
  • Privacy Policy
  • Follow on Google News
Sunday, May 18, 2025
  • Login
News Punjab
  • Home
  • Punjab
  • India
    • National
    • State News
  • World
  • Business
  • Education
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Fashion & Beauty
    • Travel
    • Food
    • Photography
  • Tech
    • App News
  • Auto
  • Sports
  • Finance/Money
  • Others
    • Agriculture
    • Science
    • Astrology
    • Press Release
    • Religion
    • Social Work
No Result
View All Result
  • Home
  • Punjab
  • India
    • National
    • State News
  • World
  • Business
  • Education
  • Entertainment
  • Lifestyle
    • Health & Fitness
    • Fashion & Beauty
    • Travel
    • Food
    • Photography
  • Tech
    • App News
  • Auto
  • Sports
  • Finance/Money
  • Others
    • Agriculture
    • Science
    • Astrology
    • Press Release
    • Religion
    • Social Work
No Result
View All Result
News Punjab
No Result
View All Result
Home Lifestyle Health & Fitness

Cord Blood transplant outperforms bone marrow transplant states a new study by ASH

by News Punjab Desk
March 31, 2021
in Health & Fitness
Reading Time: 3 mins read
A A
0
Share on FacebookShare on Twitter
  • Published in the journal – Blood Advances – the studies aim to study the efficacy of cord blood in treatment of diverse disorders

  • Studies’ outcome crucial for multi-ethnic country like India, where the chances of finding a matching donor are very low.

New Delhi: American Society of Hematology (ASH), the world’s largest professional society working to conquer blood diseases has recently released two key studies on cord blood transplants, as part of its Blood Advances journal. Led by a team of leading researchers from University of Colorado and University of Pittsburgh, the two studies have brought to foray the various benefits of cord blood transplant over bone marrow in cancerous and non-cancerous disorders. With the growing concerns among medical fraternity about finding matching bone marrow donors in a multi-ethnic country like India, the findings of the studies clearly outline the efficacy of cord blood in the treatment of diverse disorders.

In the study conducted to weigh benefits of cord blood transplant over bone marrow transplant for cancerous disorders, University of Colorado researchers compared the outcomes of matched bone marrow and double-unit cord blood transplants in adults. Amongst the 313 patients studied (190 cord blood transplant and 123 matched related donor transplant patients), the two key findings emerged. One, Chances of developing graft versus host disease were higher with bone marrow as compared to cord blood transplants and two, it was discovered that relapse rates were lower in patients who received a cord blood transplant.

RELATED POSTS

Healing Little Hearts: Dr. Prashant Bobhate Leads Early CHD Detection

Healing Little Hearts: Dr. Prashant Bobhate Leads Early CHD Detection

May 17, 2025
Dr Sunita Dube along with 21 Lakh Doctors Supports Tribunal Health law raised in Parliament by MP

Dr Sunita Dube along with 21 Lakh Doctors Supports Tribunal Health law raised in Parliament by MP

December 12, 2023

Followed by the findings of the first study, a second study on the efficacy of cord blood transplant among non-cancerous disorders was also undertaken by a team of researchers from University of Pittsburgh. The researchers successfully treated 44 children suffering from various non-cancerous & immune disorders with a combination of low dose chemotherapy and single-unit of HLA-mismatched cord blood with no cell expansion. The successful outcomes provided by this first of its kind and the largest trial showed that cord blood outperformed bone marrow in terms of graft failure, treatment related mortality and event-free survival. Also, this gives tremendous confidence to patients & doctors in a multi-ethnic country like India where the chances of finding a matching donor are very low.

Commenting on this, Dr. Sunil Bhat, MBBS, MD (Pediatrics) Mazumdar Shaw Cancer Centre, Narayana Health City, Bengaluru said, “Authors have tried a new conditioning regimen which is “reduced toxicity” hence less toxic to the patients but at the same time quite effective resulting into good outcomes in these difficult disease conditions. The application of “immune boost” post-transplant is also novel and results into better immune recovery and less complications especially of infections post cord blood transplant.”

“Another study which was published during same year gives a clear understanding on how to select a cord blood donor based on Human Leukocyte Antigens (HLA) match and also makes clear recommendations on the stem cell dose required for successful transplant. This study is also a great guide to the physicians to select cord blood donors for transplant purpose.

Other key highlights from the studies:

Study 1 – To understand the efficacy of Cord Blood transplants over bone marrow for Cancerous disorders

  • Outcomes of this study demonstrated that cancer patients undergoing cord blood transplants showed better improvement & developed lesser complications than those who received matched sibling donor transplants.
  • The overall improved recovery rate and lack of complications resulted in low costs associated with post-transplant care.
  • This treatment protocol had a distinct positive impact on the patients’ quality of life.

 

Study 2 – To understand the efficacy of Cord Blood transplants over bone marrow for non-cancerous disorders

  • The graft failure rate of <5% seen in this trial is the lowest ever reported for non-manipulated cord blood grafts in non-cancerous or even in cancerous diseases.
  • The lowest 1-year (Treatment-Related Mortality) TRM of 5%, resulting in >90% Event Free Survival (EFS) at 1 year was reported.
  • A single unit of allogeneic cord blood could be identified for each of the 44 eligible children regardless of their ethnicities, showing the unique and unparalleled suitability of cord blood grafts even without being perfectly (HLA) matched.
  • No cell expansion was required in the trial. In general, a single cord blood unit doesn’t have sufficient stem cells to treat adults.
  • No patient developed severe chronic graft versus host disease and a distinct improvement in the quality of life was reported.
  • The novel treatment protocol used in the trial prevented graft failure and aided immune reconstitution.
ShareTweetShareSendSharePinSend
Previous Post

A women-led startup develops deep-tech for reliable low-cost internet services to rural areas

Next Post

New hope for mitochondrial disorders

News Punjab Desk

News Punjab Desk

Related Posts

Healing Little Hearts: Dr. Prashant Bobhate Leads Early CHD Detection

Healing Little Hearts: Dr. Prashant Bobhate Leads Early CHD Detection

by News Punjab Desk
May 17, 2025
0

Every year, approximately 2,00,000 babies in India are born with congenital heart disease (CHD), yet less than 20% receive timely...

Dr Sunita Dube along with 21 Lakh Doctors Supports Tribunal Health law raised in Parliament by MP

Dr Sunita Dube along with 21 Lakh Doctors Supports Tribunal Health law raised in Parliament by MP

by News Punjab Desk
December 12, 2023
0

New Delhi : 12th December 2023: Renowned Radiologist Dr Sunita Dube, a revolutionary doctor has taken a ground-breaking initiative to...

Health check-up camp on 26/11 Martyrs’ Day with PM Modi’s message; Manoj Kumar Jain extended support

Health check-up camp on 26/11 Martyrs’ Day with PM Modi’s message; Manoj Kumar Jain extended support

by News Punjab Desk
November 27, 2023
0

New Delhi : In observance of the 26/11 Martyrs' Day, a mega health check-up camp was organised today, aligning with...

Narayana Health launches their First Ever Brand Campaign ‘Take Care’

Narayana Health launches their First Ever Brand Campaign ‘Take Care’

by News Punjab Desk
September 30, 2023
0

Narayana Health Group – one of India’s leading healthcare providers, committed to delivering exceptional patient care is thrilled to announce...

KareXpert achieves Ayushman Bharat Digital Mission Certification, paving the way for the digital healthcare revolution

KareXpert achieves Ayushman Bharat Digital Mission Certification, paving the way for the digital healthcare revolution

by News Punjab Desk
September 13, 2023
0

This milestone achievement positions KareXpert as a driving force behind the "Digital Healthcare Revolution" sweeping across the nation KareXpert, Jio-backed...

Next Post

New hope for mitochondrial disorders

Salt substitution is effective to reduce blood pressure in rural India

Leave a Reply Cancel reply

Your email address will not be published. Required fields are marked *

Healing Little Hearts: Dr. Prashant Bobhate Leads Early CHD Detection

Healing Little Hearts: Dr. Prashant Bobhate Leads Early CHD Detection

May 17, 2025
Lotus Herbals Launches Multimedia Campaign for Safe Sun Ultra Rx Sunscreen Serum SPF 60+

Lotus Herbals Launches Multimedia Campaign for Safe Sun Ultra Rx Sunscreen Serum SPF 60+

April 3, 2025
‘Tu Hi Meri Jaan’ Romantic Album Featuring Bollywood Actor Shantanu Bhamare & Prachi Thorat Released!

‘Tu Hi Meri Jaan’ Romantic Album Featuring Bollywood Actor Shantanu Bhamare & Prachi Thorat Released!

January 3, 2025

Categories

  • Agriculture
  • App News
  • Astrology
  • Auto
  • Business
  • Education
  • Entertainment
  • Fashion & Beauty
  • Finance/Money
  • Food
  • Health & Fitness
  • India
  • Lifestyle
  • National
  • Photography
  • Politics
  • Press Release
  • Punjab
  • Religion
  • Science
  • Social Work
  • Sports
  • State News
  • Tech
  • Travel
  • World
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Privacy Policy
  • Follow on Google News

© 2022 News Punjab

No Result
View All Result
  • About Us
  • Advertise
  • Contact Us
  • DMCA
  • Home
  • Privacy Policy

© 2022 News Punjab

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In